Molecule Details
InChIKeyDSSRVQAIWBZWON-UHFFFAOYSA-N
Compound NameN-(5-(3,5-difluorobenzyl)-1H-indazol-3-yl)-2-methoxy-4-(4-methylpiperazin-1-yl)benzamide
Canonical SMILESCOc1cc(N2CCN(C)CC2)ccc1C(=O)Nc1n[nH]c2ccc(Cc3cc(F)cc(F)c3)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.73
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P29376 LTK Homo sapiens Human PF12810 PF07714 7.9 Ki ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 7.4 Ki ChEMBL
P30291 WEE1 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.9 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.6 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.3 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.2 Ki ChEMBL
Q05397 PTK2 Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.2 Ki ChEMBL
P16591 FER Homo sapiens Human PF00611 PF07714 PF00017 6.0 Ki ChEMBL