Molecule Details
InChIKeyDSSNAGYVGTYAGH-AREMUKBSSA-N
Compound NameHpk1-IN-31
Canonical SMILESCC(C)(O)Cn1cc(-c2cnc3nc2N[C@H](CO)c2ccccc2OCCCCc2cc(ccc2C#N)N3)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL7.47
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
Q12866 MERTK Homo sapiens Human PF00041 PF00047 PF13927 PF07714 8.0 IC50 ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 7.7 IC50 ChEMBL
Q7L7X3 TAOK1 Homo sapiens Human PF00069 7.7 IC50 ChEMBL
Q92918 MAP4K1 Homo sapiens Human PF00780 PF00069 7.7 IC50 ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 7.7 IC50 ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 7.4 IC50 ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.3 IC50 ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 7.2 IC50 ChEMBL
Q8IVH8 MAP4K3 Homo sapiens Human PF00780 PF00069 7.1 IC50 ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.9 IC50 ChEMBL