Molecule Details
InChIKeyDSKYHEJWWIBREA-BETUJISGSA-N
Canonical SMILESCc1ccc(-c2cn([C@H]3CC[C@@H](N)CC3)c3ncnc(N)c23)c(F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.53
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13546 RIPK1 Homo sapiens Human PF00531 PF07714 9.6 Kd ChEMBL
O43353 RIPK2 Homo sapiens Human PF00619 PF07714 9.2 IC50 ChEMBL
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 7.8 IC50 ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 7.2 IC50 ChEMBL
Q9Y572 RIPK3 Homo sapiens Human PF00069 PF12721 7.1 Kd ChEMBL
P57059 SIK1 Homo sapiens Human PF00069 PF23312 7.0 IC50 ChEMBL
Q6XUX3 DSTYK Homo sapiens Human PF00069 6.2 Kd ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.1 IC50 ChEMBL