Molecule Details
| InChIKey | DQGTWWTUKZRUKI-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-[4-[(4-Methylphenyl)carbamoylamino]phenyl]indole-1-carboxamide |
| Canonical SMILES | Cc1ccc(NC(=O)Nc2ccc(-c3cc4ccccc4n3C(N)=O)cc2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.85 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P01127 | PDGFB | Homo sapiens | Human | PF00341 PF04692 | 8.0 | IC50 | BindingDB |
| P09619 | PDGFRB | Homo sapiens | Human | PF00047 PF13927 PF25305 PF07714 | 8.0 | IC50 | ChEMBL |
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 7.6 | IC50 | ChEMBL;BindingDB |