1-[3,5-bis[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]-3-[3-[3-[[3,5-bis[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]carbamoylamino]propyl-methylamino]propyl]urea

InChIKey	`DPRGOXVMSNDADU-UHFFFAOYSA-N`
Compound Name	1-[3,5-bis[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]-3-[3-[3-[[3,5-bis[N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]carbamoylamino]propyl-methylamino]propyl]urea
Canonical SMILES	`CC(=NNC(=N)N)c1cc(NC(=O)NCCCN(C)CCCNC(=O)Nc2cc(C(C)=NNC(=N)N)cc(C(C)=NNC(=N)N)c2)cc(C(C)=NNC(=N)N)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	16
Pfam Stratification	Homologous
Avg pChEMBL	6.33
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O43293	DAPK3	Homo sapiens	Human	PF00069	6.6	Ki	ChEMBL
P11309	PIM1	Homo sapiens	Human	PF00069	6.6	Ki	ChEMBL
Q13153	PAK1	Homo sapiens	Human	PF00786 PF00069	6.6	Ki	ChEMBL
Q05655	PRKCD	Homo sapiens	Human	PF00130 PF21494 PF00069 PF00433	6.5	Ki	ChEMBL
Q13188	STK3	Homo sapiens	Human	PF11629 PF00069	6.5	Ki	ChEMBL
P31749	AKT1	Homo sapiens	Human	PF00169 PF00069 PF00433	6.4	Ki	ChEMBL
Q9Y243	AKT3	Homo sapiens	Human	PF00169 PF00069 PF00433	6.4	Ki	ChEMBL
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	6.3	Ki	ChEMBL
P05129	PRKCG	Homo sapiens	Human	PF00130 PF00168 PF00069 PF00433	6.3	Ki	ChEMBL
P23443	RPS6KB1	Homo sapiens	Human	PF00069 PF00433	6.3	Ki	ChEMBL
Q5VT25	CDC42BPA	Homo sapiens	Human	PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433	6.3	Ki	ChEMBL
Q05513	PRKCZ	Homo sapiens	Human	PF00130 PF00564 PF00069 PF00433	6.2	Ki	ChEMBL
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	6.2	Ki	ChEMBL
P51812	RPS6KA3	Homo sapiens	Human	PF00069 PF00433	6.1	Ki	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
Q9BZL6	PRKD2	Homo sapiens	Human	PF00130 PF00169 PF00069 PF25525	6.0	Ki	ChEMBL