Molecule Details
InChIKeyDORZPJWJOBMQKC-UHFFFAOYSA-N
Compound Name(3-(4-Imino-3,5,12-triazatetracyclo(9.7.0.0^(2,7).0^(13,18))octadeca-1(11),2,6,13,15,17-hexaen-16-yl)prop-2-yn-1-yl)dimethylamine
Canonical SMILESCN(C)CC#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.76
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y2I7 PIKFYVE Homo sapiens Human PF00118 PF00610 PF01363 PF01504 8.4 IC50 ChEMBL;BindingDB
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 7.0 IC50 ChEMBL
Q86YV6 MYLK4 Homo sapiens Human PF00069 6.9 IC50 ChEMBL
Q15746 MYLK Homo sapiens Human PF16620 PF00041 PF07679 PF00069 6.6 IC50 ChEMBL;BindingDB
P49760 CLK2 Homo sapiens Human PF00069 6.5 IC50 ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.4 IC50 ChEMBL
P49759 CLK1 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
O75716 STK16 Homo sapiens Human PF00069 6.2 IC50 ChEMBL