Molecule Details
InChIKeyDORQSUNHACTGLQ-QFIPXVFZSA-N
Compound Name2-[(2R)-4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]-1H-indole-5-carbonitrile
Canonical SMILESCOc1ccc(F)cc1C(C)(C)C[C@@](O)(Cc1cc2cc(C#N)ccc2[nH]1)C(F)(F)F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.64
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P04150 NR3C1 Homo sapiens Human PF02155 PF00104 PF00105 8.8 IC50 ChEMBL;BindingDB
P08235 NR3C2 Homo sapiens Human PF00104 PF00105 7.3 IC50 ChEMBL;BindingDB
P06401 PGR Homo sapiens Human PF00104 PF02161 PF00105 6.8 IC50 ChEMBL;BindingDB