DMKUCUYQRJKWJF-MEMLXQNLSA-N

InChIKey	`DMKUCUYQRJKWJF-MEMLXQNLSA-N`
Canonical SMILES	`O[C@H]1CC[C@H](Nc2nc(Nc3cc4ccccc4cn3)cc(C(F)(F)c3ccc(F)cc3)n2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.43
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q08881	ITK	Homo sapiens	Human	PF00779 PF00169 PF07714 PF00017 PF00018	8.2	Ki	ChEMBL;BindingDB
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.1	Ki	ChEMBL;BindingDB
P06239	LCK	Homo sapiens	Human	PF07714 PF00017 PF00018	7.0	Ki	ChEMBL