Molecule Details
InChIKeyDMJWENQHWZZWDF-PKOBYXMFSA-N
Compound NameEcopipam
Canonical SMILESCN1CCc2cc(Cl)c(O)cc2[C@H]2c3ccccc3CC[C@@H]21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.88
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12273
Drug NameEcopipam
CAS Number112108-01-7
Groups investigational
ATC Codes nan
DescriptionEcopipam has been used in trials studying the treatment of Tourette's Syndrome, Lesch-Nyhan Disease, Pathological Gambling, and Self-injurious Behavior.

Categories: Antipsychotic Agents Central Nervous System Agents Central Nervous System Depressants Dopamine Agents Dopamine Antagonists Heterocyclic Compounds, Fused-Ring Neurotoxic agents Neurotransmitter Agents Psychotropic Drugs Tranquilizing Agents
Cross-references: BindingDB: 50004823 ChEBI: 93645 CHEMBL298406 ChemSpider: 97053 PubChem:107930 PubChem:347828544 Wikipedia: Ecopipam ZINC: ZINC000000003897
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P21728 DRD1 Homo sapiens Human PF00001 8.9 Ki ChEMBL;BindingDB
P21918 DRD5 Homo sapiens Human PF00001 8.7 Ki ChEMBL;BindingDB
P14416 DRD2 Homo sapiens Human PF00001 6.0 Ki ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P21728 DRD1 D(1A) dopamine receptor modulator targets