(4R)-N-[3-[4-(2-cyano-4-fluorophenyl)piperidin-1-yl]propyl]-4-(3,4-difluorophenyl)-1,6-dimethyl-2-oxo-3,4-dihydropyridine-5-carboxamide

InChIKey	`DLMPCEBSXNLTAT-XMMPIXPASA-N`
Compound Name	(4R)-N-[3-[4-(2-cyano-4-fluorophenyl)piperidin-1-yl]propyl]-4-(3,4-difluorophenyl)-1,6-dimethyl-2-oxo-3,4-dihydropyridine-5-carboxamide
Canonical SMILES	`CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Homologous
Avg pChEMBL	6.94
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P35348	ADRA1A	Homo sapiens	Human	PF00001	9.1	pIC50	TTD_MultiTarget
P18089	ADRA2B	Homo sapiens	Human	PF00001	6.5	Ki	ChEMBL;BindingDB
P35368	ADRA1B	Homo sapiens	Human	PF00001	6.4	Ki	ChEMBL;BindingDB
P35367	HRH1	Homo sapiens	Human	PF00001	6.4	Ki	ChEMBL;BindingDB
P25100	ADRA1D	Homo sapiens	Human	PF00001	6.2	Ki	ChEMBL;BindingDB