N-[6-methyl-5-[[2-(1-methylpyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-5-oxo-6-azaspiro[3.4]octane-6-carboxamide

InChIKey	`DKIXPZZJZUEUGI-UHFFFAOYSA-N`
Compound Name	N-[6-methyl-5-[[2-(1-methylpyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-5-oxo-6-azaspiro[3.4]octane-6-carboxamide
Canonical SMILES	`Cc1nc(NC(=O)N2CCC3(CCC3)C2=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.58
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P07333	CSF1R	Homo sapiens	Human	PF00047 PF25305 PF07714	8.9	IC50	ChEMBL;BindingDB
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	7.5	IC50	ChEMBL;BindingDB
P16234	PDGFRA	Homo sapiens	Human	PF07679 PF25305 PF07714	6.3	IC50	ChEMBL;BindingDB