Molecule Details
| InChIKey | DKEHSDCAAWFLHB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[5-[4-(4-Chlorophenyl)piperazino]sulfonyl-2-methyl-indolin-1-yl]propan-1-one |
| Canonical SMILES | CCC(=O)N1c2ccc(S(=O)(=O)N3CCN(c4ccc(Cl)cc4)CC3)cc2CC1C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.15 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P01375 | TNF | Homo sapiens | Human | PF00229 | 6.2 | IC50 | ChEMBL;BindingDB |
| Q9HC29 | NOD2 | Homo sapiens | Human | PF00619 PF13516 PF05729 PF17776 PF17779 | 6.2 | IC50 | ChEMBL;BindingDB |
| Q9Y239 | NOD1 | Homo sapiens | Human | PF00619 PF13516 PF05729 PF17776 PF17779 | 6.0 | IC50 | ChEMBL |