1-{[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methyl]-amino}-5-naphthalen-1-yl-1,2,3,6-tetrahydro-pyridine-4-carbonitrile

InChIKey	`DJYOAYPWIWACRH-UHFFFAOYSA-N`
Compound Name	1-{[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methyl]-amino}-5-naphthalen-1-yl-1,2,3,6-tetrahydro-pyridine-4-carbonitrile
Canonical SMILES	`Cn1cncc1C(NN1CCC(C#N)=C(c2cccc3ccccc23)C1)c1ccc(C#N)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.27
Source	ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49354	FNTA	Homo sapiens	Human	PF01239	9.3	pIC50	TTD_MultiTarget
P49356	FNTB	Homo sapiens	Human	PF00432	9.3	IC50	ChEMBL
P53609	PGGT1B	Homo sapiens	Human	PF00432	6.2	IC50	ChEMBL