Molecule Details
InChIKeyDJUSDFVEBBYFFL-UHFFFAOYSA-N
Compound Name6,9-dichloro[1]benzothieno[3,2-d]pyrimidin-4(3H)-one
Canonical SMILESO=c1[nH]cnc2c1sc1c(Cl)ccc(Cl)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)27
Pfam Stratification Cross-Family
Avg pChEMBL6.41
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (27)
Target Gene Organism Category Pfam pChEMBL Type Source
Q86V86 PIM3 Homo sapiens Human PF00069 8.0 Ki ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.0 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.9 Ki ChEMBL;BindingDB
O43293 DAPK3 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.8 Ki ChEMBL;BindingDB
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q96KB5 PBK Homo sapiens Human PF00069 6.5 Ki ChEMBL
P43405 SYK Homo sapiens Human PF07714 PF00017 6.5 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.3 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q06187 BTK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.2 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.1 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.0 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.0 Ki ChEMBL
P07332 FES Homo sapiens Human PF00611 PF07714 PF00017 6.0 Ki ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 6.0 Ki ChEMBL
P30530 AXL Homo sapiens Human PF00041 PF13927 PF07714 6.0 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.0 Ki ChEMBL
Q8IW41 MAPKAPK5 Homo sapiens Human PF00069 6.0 Ki ChEMBL