Molecule Details
| InChIKey | DJNNZKJZFCRFRX-FTJBHMTQSA-N |
|---|---|
| Compound Name | N-(Benzylsulfonyl)-3-Cyclohexyl-D-Alanyl-N-(4-Carbamimidoylbenzyl)-L-Prolinamide |
| Canonical SMILES | N=C(N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC2CCCCC2)NS(=O)(=O)Cc2ccccc2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.37 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00734 | F2 | Homo sapiens | Human | PF00594 PF00051 PF09396 PF00089 | 10.0 | Ki | ChEMBL;BindingDB |
| O60235 | TMPRSS11D | Homo sapiens | Human | PF01390 PF00089 | 7.0 | Ki | ChEMBL;BindingDB |
| Q8IU80 | TMPRSS6 | Homo sapiens | Human | PF00057 PF01390 PF00089 | 6.4 | Ki | ChEMBL;BindingDB |
| Q9Y5Y6 | ST14 | Homo sapiens | Human | PF00431 PF00057 PF01390 PF00089 | 6.1 | Ki | ChEMBL;BindingDB |