Molecule Details
InChIKeyDJKJVWJQAVGLHJ-YPMHNXCESA-N
Compound Name(+/-)-(7aR*,11aR*)-5,6,7a,8,9,10,11,11a-Octahydro-4-(1-piperazinyl)-benzofuran[2,3-h]quinazolin-2-amine
Canonical SMILESNc1nc2c(c(N3CCNCC3)n1)CCC1=C2[C@@H]2CCCC[C@@H]2O1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.53
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P32246 CCR1 Homo sapiens Human PF00001 10.2 IC50 ChEMBL
P37288 AVPR1A Homo sapiens Human PF00001 PF08983 8.5 IC50 ChEMBL
P21452 TACR2 Homo sapiens Human PF00001 8.4 IC50 ChEMBL
Q9H3N8 HRH4 Homo sapiens Human PF00001 7.7 Ki ChEMBL;BindingDB
P41595 HTR2B Homo sapiens Human PF00001 6.5 Ki ChEMBL
P46098 HTR3A Homo sapiens Human PF02931 PF02932 6.5 Ki ChEMBL
Q99720 SIGMAR1 Homo sapiens Human PF04622 6.3 Ki ChEMBL
Q9Y5N1 HRH3 Homo sapiens Human PF00001 6.0 Ki ChEMBL;BindingDB