Molecule Details
InChIKeyDJEIHHYCDCTAAH-UHFFFAOYSA-N
Compound NameMofezolac
Canonical SMILESCOc1ccc(-c2noc(CC(=O)O)c2-c2ccc(OC)cc2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.61
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21153
Drug NameMofezolac
CAS Number78967-07-4
Groups experimental
ATC Codes nan
DescriptionMofezolac is a small molecule drug. The usage of the INN stem '-ac' in the name indicates that Mofezolac is a anti-inflammatory agent, ibufenac derivative. Mofezolac has a monoisotopic molecular weight of 339.11 Da.

Categories: Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Antirheumatic Agents Cyclooxygenase 1 Cyclooxygenase Inhibitors Enzyme Inhibitors Peripheral Nervous System Agents Sensory System Agents
Cross-references: BindingDB: 50376383 ChEBI: 31860 CHEMBL259972 PDB: 63X RxCUI: 11469 ZINC: ZINC000000003767
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P23219 PTGS1 Homo sapiens Human PF03098 8.8 IC50 ChEMBL;BindingDB
P35354 PTGS2 Homo sapiens Human PF03098 6.4 IC50 ChEMBL;BindingDB