Molecule Details
| InChIKey | DHSSDEDRBUKTQY-UHFFFAOYSA-N |
|---|---|
| Compound Name | Talipexole |
| Canonical SMILES | C=CCN1CCc2nc(N)sc2CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.7 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB20211 |
|---|---|
| Drug Name | Talipexole |
| CAS Number | 101626-70-4 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Talipexole is a small molecule drug. Talipexole has a monoisotopic molecular weight of 209.1 Da. |
Categories: Adrenergic Agents Adrenergic Agonists Adrenergic alpha-Agonists Antidepressive Agents Central Nervous System Agents Central Nervous System Depressants Dopamine Agents Dopamine Agonists Neurotransmitter Agents Psychotropic Drugs
Cross-references: BindingDB: 86053 ChEBI: 93327 CHEMBL279085 ZINC: ZINC000000006644
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 7.2 | Ki | ChEMBL;BindingDB |
| P08913 | ADRA2A | Homo sapiens | Human | PF00001 | 6.9 | Ki | BindingDB |
| P18825 | ADRA2C | Homo sapiens | Human | PF00001 | 6.7 | Ki | BindingDB |
| P18089 | ADRA2B | Homo sapiens | Human | PF00001 | 6.7 | Ki | BindingDB |
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 6.5 | Ki | BindingDB |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 6.2 | Ki | ChEMBL;BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P14416 | DRD2 | D(2) dopamine receptor | agonist | targets |