(+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-2-yl)-tetrahydrofuran-3-carboxamide

InChIKey	`DGTWHZKHMUDXOY-UHFFFAOYSA-N`
Compound Name	(+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-2-yl)-tetrahydrofuran-3-carboxamide
Canonical SMILES	`O=C(Nc1cc(-c2ccnc(Nc3ccc(F)cc3)c2)ccn1)C1CCOC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.36
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P53779	MAPK10	Homo sapiens	Human	PF00069	8.5	IC50	ChEMBL;BindingDB
P45983	MAPK8	Homo sapiens	Human	PF00069	7.3	IC50	ChEMBL;BindingDB
Q16539	MAPK14	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL;BindingDB