Molecule Details
| InChIKey | DGHWUYQHCWDSCX-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[4-[1-(hydroxyamino)-1-oxohexan-2-yl]-1,3-thiazol-2-yl]-6-(phenoxymethyl)pyridine-2-carboxamide |
| Canonical SMILES | CCCCC(C(=O)NO)c1csc(NC(=O)c2cccc(COc3ccccc3)n2)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.67 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P54750 | PDE1A | Homo sapiens | Human | PF00233 PF08499 | 6.7 | IC50 | ChEMBL |
| Q01064 | PDE1B | Homo sapiens | Human | PF00233 PF08499 | 6.7 | IC50 | ChEMBL;BindingDB |
| Q14123 | PDE1C | Homo sapiens | Human | PF00233 PF08499 | 6.7 | IC50 | ChEMBL |
| O76074 | PDE5A | Homo sapiens | Human | PF01590 PF00233 | 6.6 | IC50 | ChEMBL;BindingDB |