N-(2-chloro-4-methylthiophen-3-yl)-2-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

InChIKey	`DFZKXFCZKLBBRG-UHFFFAOYSA-N`
Compound Name	N-(2-chloro-4-methylthiophen-3-yl)-2-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
Canonical SMILES	`Cc1nc(Nc2ncc(C(=O)Nc3c(C)csc3Cl)s2)cc(N2CCN(C)CC2)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.67
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P57059	SIK1	Homo sapiens	Human	PF00069 PF23312	7.9	IC50	ChEMBL;BindingDB
Q9H0K1	SIK2	Homo sapiens	Human	PF00069 PF23312	7.9	IC50	ChEMBL;BindingDB
Q9Y2K2	SIK3	Homo sapiens	Human	PF00069 PF23312	7.2	IC50	ChEMBL;BindingDB