Molecule Details
InChIKeyDDNCQMVWWZOMLN-IRLDBZIGSA-N
Canonical SMILESCCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c(n1c1ccccc41)[C@@H]32
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.63
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12131
Drug NameVinpocetine
CAS Number42971-09-5
Groups investigational
ATC Codes N06BX18
DescriptionVinpocetine has been investigated for the treatment of Epilepsy.

Categories: Agents causing hyperkalemia Alkaloids Antiarrhythmic agents Anticonvulsants Bradycardia-Causing Agents Calcium Channel Blockers Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Compounds used in a research, industrial, or household setting Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Indole Alkaloids Indoles Indolizidines Indolizines Nervous System Neuroprotective Agents Nootropic Agents Phosphodiesterase Inhibitors Protective Agents Psychoanaleptics Psychostimulants, Agents Used for ADHD and Nootropics Secologanin Tryptamine Alkaloids Vasodilating Agents
Cross-references: BindingDB: 50059033 ChEBI: 32297 CHEMBL71752 ChemSpider: 392007 PDB: T7F PubChem:443955 PubChem:347828430 RxCUI: 24506 Wikipedia: Vinpocetine ZINC: ZINC000019796031
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P54750 PDE1A Homo sapiens Human PF00233 PF08499 7.8 Kd BindingDB
Q12809 KCNH2 Homo sapiens Human PF00027 PF00520 PF13426 7.4 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P08684 CYP3A4 Cytochrome P450 3A4 substrate enzymes