2-Amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]thieno[2,3-d]pyrimidin-4(3H)-one

InChIKey	`DCYZSPHKXACGQZ-UHFFFAOYSA-N`
Compound Name	2-Amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]thieno[2,3-d]pyrimidin-4(3H)-one
Canonical SMILES	`Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc([N+](=O)[O-])cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.82
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04818	TYMS	Homo sapiens	Human	PF00303	7.0	IC50	ChEMBL;BindingDB
P00374	DHFR	Homo sapiens	Human	PF00186	6.2	pIC50	TTD_MultiTarget
Q07422		Toxoplasma gondii	Pathogen	PF00186 PF00303	7.2	IC50	ChEMBL;BindingDB