Molecule Details
InChIKeyDCTBPIBEQFLAOQ-UHFFFAOYSA-N
Compound Name1-(16-Amino-11-thia-13,15-diazatetracyclo[8.7.0.02,7.012,17]heptadeca-1(10),2(7),3,5,12,14,16-heptaen-5-yl)-3-(2-methylphenyl)urea
Canonical SMILESCc1ccccc1NC(=O)Nc1ccc2c(c1)CCc1sc3ncnc(N)c3c1-2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL6.63
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 8.1 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 7.4 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 7.2 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.7 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.4 Ki ChEMBL
P30530 AXL Homo sapiens Human PF00041 PF13927 PF07714 6.2 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.1 Ki ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.0 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.0 Ki ChEMBL
Q9UBE8 NLK Homo sapiens Human PF00069 6.0 Ki ChEMBL