Molecule Details
| InChIKey | DBWPFHJYSTVBCZ-BYPYZUCNSA-N |
|---|---|
| Compound Name | (alphaS)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid |
| Canonical SMILES | N[C@@H](Cn1cc(F)c(=O)[nH]c1=O)C(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.17 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB02966 |
|---|---|
| Drug Name | Fluoro-Willardiine |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50060635 ChEBI: 42549 CHEMBL123132 ChemSpider: 112461 PDB: FWD PubChem:126569 PubChem:46506706 ZINC: ZINC000002530708
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P42261 | GRIA1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.8 | Ki | ChEMBL;BindingDB |
| P42262 | GRIA2 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.6 | Ki | ChEMBL;BindingDB |
| P42263 | GRIA3 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.8 | Ki | BindingDB |
| P48058 | GRIA4 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.5 | Ki | ChEMBL;BindingDB |