4-[4-[2-[[7-Amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]piperazin-1-yl]benzenesulfonamide

InChIKey	`DBSSNIVKOMKZGN-UHFFFAOYSA-N`
Compound Name	4-[4-[2-[[7-Amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]piperazin-1-yl]benzenesulfonamide
Canonical SMILES	`Nc1nc(NCCN2CCN(c3ccc(S(N)(=O)=O)cc3)CC2)nc2sc(-c3ccco3)nc12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.86
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P29275	ADORA2B	Homo sapiens	Human	PF00001	9.5	IC50	ChEMBL;BindingDB
P29274	ADORA2A	Homo sapiens	Human	PF00001	7.1	Ki	ChEMBL;BindingDB
P30542	ADORA1	Homo sapiens	Human	PF00001	7.0	Ki	ChEMBL;BindingDB