Molecule Details
InChIKeyDBRXOUCRJQVYJQ-CKNDUULBSA-N
Compound NameWithaferin A
Canonical SMILESCC1=C(CO)C(=O)O[C@@H]([C@@H](C)[C@H]2CC[C@H]3[C@@H]4C[C@H]5O[C@]56[C@@H](O)C=CC(=O)[C@]6(C)[C@H]4CC[C@]23C)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL7.06
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P19838 NFKB1 Homo sapiens Human PF12796 PF00531 PF16179 PF00554 7.3 IC50 ChEMBL
Q00653 NFKB2 Homo sapiens Human PF00023 PF12796 PF00531 PF16179 PF00554 7.3 IC50 ChEMBL
Q04206 RELA Homo sapiens Human PF16179 PF00554 7.3 IC50 ChEMBL
P0DTD1 rep Severe acute respiratory syndrome coronavirus 2 Pathogen PF13087 PF16251 PF11501 PF12379 PF12124 PF11633 PF06471 PF06460 PF09401 PF20631 PF20633 PF20632 PF19215 PF19216 PF19219 PF19211 PF19218 PF16348 PF19217 PF19213 PF08716 PF08717 PF08710 PF08715 PF06478 PF01661 PF05409 PF00680 6.2 IC50 ChEMBL