3-Acetamido-4,5-dichloro-1-benzothiophene-2-carboxamide

InChIKey	`DBKQWGCVGCVPIP-UHFFFAOYSA-N`
Compound Name	3-Acetamido-4,5-dichloro-1-benzothiophene-2-carboxamide
Canonical SMILES	`CC(=O)Nc1c(C(N)=O)sc2ccc(Cl)c(Cl)c12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	21
Pfam Stratification	Cross-Family
Avg pChEMBL	6.35
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	7.1	Ki	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	7.0	Ki	ChEMBL
Q9UEE5	STK17A	Homo sapiens	Human	PF00069	6.9	Ki	ChEMBL
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	6.6	Ki	ChEMBL
Q9H2X6	HIPK2	Homo sapiens	Human	PF00069	6.6	Ki	ChEMBL
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	6.4	Ki	ChEMBL
P49760	CLK2	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
O00311	CDC7	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q13976	PRKG1	Homo sapiens	Human	PF00027 PF16808 PF00069	6.3	Ki	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q96KB5	PBK	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
P08922	ROS1	Homo sapiens	Human	PF00041 PF07714	6.2	Ki	ChEMBL
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	6.2	Ki	ChEMBL
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	6.2	Ki	ChEMBL
Q16513	PKN2	Homo sapiens	Human	PF02185 PF00069 PF00433	6.2	Ki	ChEMBL
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.1	Ki	ChEMBL
O95819	MAP4K4	Homo sapiens	Human	PF00780 PF00069	6.1	Ki	ChEMBL
P06493	CDK1	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
O94806	PRKD3	Homo sapiens	Human	PF00130 PF00169 PF00069 PF25525	6.0	Ki	ChEMBL
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	6.0	Ki	ChEMBL
P48730	CSNK1D	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL