2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-N-(1,3,5-trimethylpyrazol-4-yl)-1,3-thiazole-5-carboxamide

InChIKey	`DBHZLVWJMDYRBG-UHFFFAOYSA-N`
Compound Name	2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-N-(1,3,5-trimethylpyrazol-4-yl)-1,3-thiazole-5-carboxamide
Canonical SMILES	`Cc1nc(Nc2ncc(C(=O)Nc3c(C)nn(C)c3C)s2)cc(N2CCN(CCO)CC2)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.23
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	7.6	IC50	ChEMBL;BindingDB
P00519	ABL1	Homo sapiens	Human	PF08919 PF07714 PF00017 PF00018	7.5	IC50	ChEMBL;BindingDB
P14867	GABRA1	Homo sapiens	Human	PF02931 PF02932	6.5	IC50	BindingDB