InChIKey	DBABZHXKTCFAPX-UHFFFAOYSA-N
Canonical SMILES	CCCN(CCC)S(=O)(=O)c1ccc(C(=O)O)cc1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	6.41
Source	ChEMBL;BindingDB

DrugBank ID	DB01032
Drug Name	Probenecid
CAS Number	57-66-9
Groups	approved investigational
ATC Codes	M04AB01 G01AE10 M04AC51
Description	The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to an...

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Categories: Adjuvants, Pharmaceutic Amides Antigout Preparations Antirheumatic Agents Compounds used in a research, industrial, or household setting Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C8 Inducers Cytochrome P-450 CYP2C8 Inducers (strength unknown) Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strength unknown) Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Drugs that are Mainly Renally Excreted Genito Urinary System and Sex Hormones Gynecological Antiinfectives and Antiseptics Musculo-Skeletal System OAT1/SLC22A6 inhibitors OAT3/SLC22A8 Inhibitors OCT1 inhibitors OCT2 Inhibitors Pharmaceutic Aids Pharmaceutical Preparations Preparations Increasing Uric Acid Excretion Preparations With No Effect on Uric Acid Metabolism Sulfonamides Sulfones Sulfur Compounds UGT1A1 Inhibitors Uricosuric Agents

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Cross-references: BindingDB: 50206509 ChEBI: 8426 CHEMBL897 ChemSpider: 4742 Drugs Product Database (DPD): 9108 Guide to Pharmacology: 4357 IUPHAR: 4357 C07372 D00475 PDB: RTO PharmGKB: PA451106 PubChem:4911 PubChem:46506554 RxCUI: 8698 Therapeutic Targets Database: DAP001292 Wikipedia: Probenecid ZINC: ZINC000000001982