Molecule Details
InChIKeyDAFVWYIPVOQCBO-UHFFFAOYSA-N
Compound NameUS10544143, Example 233
Canonical SMILESCc1c(-c2[nH]c3ccc(C4CCC(NC5COC5)CC4)nc3c2C(C)C)cn2cnnc2c1C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.57
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9NYK1 TLR7 Homo sapiens Human PF13855 PF01582 8.4 IC50 ChEMBL;BindingDB
Q9NR97 TLR8 Homo sapiens Human PF13855 PF01582 8.0 IC50 ChEMBL;BindingDB
Q9NR96 TLR9 Homo sapiens Human PF18837 PF13516 PF13855 PF01582 6.4 IC50 ChEMBL;BindingDB