Molecule Details
| InChIKey | DABGHULKCXXLEE-MAUKXSAKSA-N |
|---|---|
| Compound Name | 4-(3-Allyl-2,5-dioxo-imidazolidin-1-yl)-1-(4-butoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide |
| Canonical SMILES | C=CCn1cc(O)n([C@H]2C[C@H](C(=O)NO)N(S(=O)(=O)c3ccc(OCCCC)cc3)C2)c1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.47 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P45452 | MMP13 | Homo sapiens | Human | PF00045 PF00413 PF01471 | 9.4 | IC50 | BindingDB |
| P08254 | MMP3 | Homo sapiens | Human | PF00045 PF00413 PF01471 | 8.2 | IC50 | BindingDB |
| P03956 | MMP1 | Homo sapiens | Human | PF00045 PF00413 PF01471 | 6.3 | IC50 | BindingDB |
| P09237 | MMP7 | Homo sapiens | Human | PF00413 PF01471 | 6.0 | IC50 | BindingDB |