Molecule Details
InChIKeyCZZCAOGIEGXMBZ-UHFFFAOYSA-N
Compound Name3-(1H-Indazol-5-yl)-N-propylimidazo(1,2-b)pyridazin-6-amine
Canonical SMILESCCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.96
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
Q8TF76 HASPIN Homo sapiens Human PF12330 8.7 IC50 ChEMBL;BindingDB
P11309 PIM1 Homo sapiens Human PF00069 7.5 IC50 ChEMBL
P49674 CSNK1E Homo sapiens Human PF00069 7.0 IC50 ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.9 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.9 IC50 ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.8 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.7 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 6.7 IC50 ChEMBL
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 6.2 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.2 IC50 ChEMBL