2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]benzamide

InChIKey	`CZQVOIDVDAVDFW-UHFFFAOYSA-N`
Compound Name	2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]benzamide
Canonical SMILES	`COc1ccc(-c2cc3nccn3c(Nc3ccccc3C(N)=O)n2)cc1OC`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	18
Pfam Stratification	Cross-Family
Avg pChEMBL	6.94
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P43405	SYK	Homo sapiens	Human	PF07714 PF00017	7.9	Ki	ChEMBL
Q13882	PTK6	Homo sapiens	Human	PF07714 PF00017 PF00018	7.5	Ki	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.5	Ki	ChEMBL
O14965	AURKA	Homo sapiens	Human	PF00069	7.4	Ki	ChEMBL
P51451	BLK	Homo sapiens	Human	PF07714 PF00017 PF00018	7.4	Ki	ChEMBL
P08922	ROS1	Homo sapiens	Human	PF00041 PF07714	7.2	Ki	ChEMBL
P06239	LCK	Homo sapiens	Human	PF07714 PF00017 PF00018	7.1	Ki	ChEMBL
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	7.1	Ki	ChEMBL
Q9H2G2	SLK	Homo sapiens	Human	PF00069 PF12474	7.0	Ki	ChEMBL
Q12851	MAP4K2	Homo sapiens	Human	PF00780 PF00069	6.9	Ki	ChEMBL
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.8	Ki	ChEMBL
Q06187	BTK	Homo sapiens	Human	PF00779 PF00169 PF07714 PF00017 PF00018	6.8	Ki	ChEMBL
P07948	LYN	Homo sapiens	Human	PF07714 PF00017 PF00018	6.7	Ki	ChEMBL
P07949	RET	Homo sapiens	Human	PF00028 PF07714 PF17756 PF17812 PF17813 PF22540	6.7	Ki	ChEMBL
P16591	FER	Homo sapiens	Human	PF00611 PF07714 PF00017	6.5	Ki	ChEMBL
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	6.3	Ki	ChEMBL
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.1	Ki	ChEMBL
Q16513	PKN2	Homo sapiens	Human	PF02185 PF00069 PF00433	6.0	Ki	ChEMBL