Molecule Details
InChIKeyCZIGMBNEFWBEMD-UHFFFAOYSA-N
Compound Name2-pyridin-4-yl-1H-benzimidazole-4-carboxamide
Canonical SMILESNC(=O)c1cccc2[nH]c(-c3ccncc3)nc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Homologous
Avg pChEMBL6.64
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
Q8TDC3 BRSK1 Homo sapiens Human PF21122 PF00069 PF21115 7.6 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 7.4 Ki ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.1 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.0 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.8 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.5 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q96KB5 PBK Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q16512 PKN1 Homo sapiens Human PF02185 PF00069 PF00433 6.3 Ki ChEMBL;BindingDB
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL
P15735 PHKG2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 6.0 Ki ChEMBL