InChIKey	CYQFCXCEBYINGO-IAGOWNOFSA-N
Compound Name	Tetrahydrocannabinol
Canonical SMILES	CCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.21
Source	BindingDB;ChEMBL

DrugBank ID	DB00470
Drug Name	Dronabinol
CAS Number	1972-08-3
Groups	approved illicit investigational
ATC Codes	A04AD10
Description	Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in t...

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Categories: Agents producing tachycardia Alimentary Tract and Metabolism Analgesics Analgesics, Non-Narcotic Antiemetics and Antinauseants BCRP/ABCG2 Inhibitors Cannabinoid Receptor Agonists Cannabinoids and similars Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) Cytochrome P-450 CYP2A6 Inhibitors Cytochrome P-450 CYP2A6 Inhibitors (strength unknown) Cytochrome P-450 CYP2B6 Inhibitors Cytochrome P-450 CYP2B6 Inhibitors (strength unknown) Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 CYP2C19 inhibitors (strength unknown) Cytochrome P-450 CYP2C9 Inducers Cytochrome P-450 CYP2C9 Inducers (strength unknown) Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Inhibitors Cytochrome P-450 CYP3A5 Inhibitors (weak) Cytochrome P-450 CYP3A7 Inhibitors Cytochrome P-450 CYP3A7 Inhibitors (weak) Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Hallucinogens Hormones, Hormone Substitutes, and Hormone Antagonists Miscellaneous Antiemetics Neurotransmitter Agents P-glycoprotein inhibitors Peripheral Nervous System Agents Psychotropic Drugs Sensory System Agents Terpenes UGT1A1 Substrates UGT1A3 substrates UGT1A9 Substrates

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Cross-references: BindingDB: 60994 ChEBI: 66964 CHEMBL465 ChemSpider: 15266 Drugs Product Database (DPD): 13359 Guide to Pharmacology: 2424 IUPHAR: 2424 C06972 D00306 PDB: TCI PharmGKB: PA449421 PubChem:16078 PubChem:46508472 RxCUI: 10402 Therapeutic Targets Database: DAP000207 Wikipedia: Dronabinol ZINC: ZINC000001530625