Molecule Details
| InChIKey | CYLDJPVEBVIXNB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-Amino-4-[4-[4-(dimethylcarbamoyl)phenyl]-1,4-diazepan-1-yl]thieno[2,3-b]pyridine-2-carboxamide |
| Canonical SMILES | CN(C)C(=O)c1ccc(N2CCCN(c3ccnc4sc(C(N)=O)c(N)c34)CC2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.84 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9BWU1 | CDK19 | Homo sapiens | Human | PF00069 | 7.6 | IC50 | ChEMBL |
| P49336 | CDK8 | Homo sapiens | Human | PF00069 | 7.6 | IC50 | ChEMBL |
| P48729 | CSNK1A1 | Homo sapiens | Human | PF00069 | 6.6 | Kd | ChEMBL |
| Q9BVS4 | RIOK2 | Homo sapiens | Human | PF01163 PF09202 | 6.6 | Kd | ChEMBL |
| P48730 | CSNK1D | Homo sapiens | Human | PF00069 | 6.5 | Kd | ChEMBL |
| P49674 | CSNK1E | Homo sapiens | Human | PF00069 | 6.1 | Kd | ChEMBL |