3-(4-(4-(Hydroxymethyl)thiazol-2-yl)pyrimidin-2-ylamino)-5-(trifluoromethyl)phenol

InChIKey	`CXXHIMHTNIDPAR-UHFFFAOYSA-N`
Compound Name	3-(4-(4-(Hydroxymethyl)thiazol-2-yl)pyrimidin-2-ylamino)-5-(trifluoromethyl)phenol
Canonical SMILES	`OCc1csc(-c2ccnc(Nc3cc(O)cc(C(F)(F)F)c3)n2)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.67
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P43405	SYK	Homo sapiens	Human	PF07714 PF00017	7.2	IC50	ChEMBL;BindingDB
P43403	ZAP70	Homo sapiens	Human	PF07714 PF00017	6.2	Ki	ChEMBL;BindingDB
P24941	CDK2	Homo sapiens	Human	PF00069	Clinical	TTD_MultiTarget	TTD_MultiTarget