Molecule Details
| InChIKey | CWWKTGHWIFDKSB-DAXSKMNVSA-N |
|---|---|
| Compound Name | polyandrocarpamine A |
| Canonical SMILES | COc1cc(/C=C2\N=C(N)NC2=O)ccc1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.16 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 6.3 | IC50 | ChEMBL |
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 6.3 | IC50 | ChEMBL |
| P49760 | CLK2 | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL |
| Q3I4V7 | CAN2 | Cryptococcus neoformans | Pathogen | PF00484 | 6.0 | Ki | ChEMBL |
| P96878 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Pathogen | PF00484 PF00916 | 6.0 | Ki | ChEMBL | |
| Q5AJ71 | NCE103 | Candida albicans (strain SC5314 / ATCC MYA-2876) | Pathogen | PF00484 | 6.0 | Ki | ChEMBL |