Molecule Details
| InChIKey | CWPNCIOMBLFPGU-UHFFFAOYSA-N |
|---|---|
| Compound Name | Dimethyl 6,7-dimethoxy-1-[2-(1-oxo-4-pyridin-3-ylphthalazin-2-yl)-4-pyridinyl]naphthalene-2,3-dicarboxylate |
| Canonical SMILES | COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2ccnc(-n3nc(-c4cccnc4)c4ccccc4c3=O)c2)c1C(=O)OC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.82 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 6.8 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 6.8 | IC50 | ChEMBL;BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 6.8 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 6.8 | IC50 | ChEMBL |