Molecule Details
InChIKeyCWJLAVRXVFHDSJ-UHFFFAOYSA-N
Compound Name4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-N-methylbenzamide
Canonical SMILESCNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(-c4ccc5nc(C)oc5c4)c[nH]c3n2)c(OC)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL6.77
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P49760 CLK2 Homo sapiens Human PF00069 8.1 IC50 ChEMBL;BindingDB
P33981 TTK Homo sapiens Human PF00069 8.1 IC50 ChEMBL;BindingDB
O43781 DYRK3 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
Q13627 DYRK1A Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
Q16816 PHKG1 Homo sapiens Human PF00069 6.9 IC50 ChEMBL;BindingDB
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.8 IC50 ChEMBL;BindingDB
P08684 CYP3A4 Homo sapiens Human PF00067 6.5 IC50 ChEMBL;BindingDB
P49759 CLK1 Homo sapiens Human PF00069 6.5 IC50 ChEMBL;BindingDB
P49761 CLK3 Homo sapiens Human PF00069 6.5 IC50 ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
P53779 MAPK10 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
Q96RR4 CAMKK2 Homo sapiens Human PF00069 6.2 IC50 ChEMBL;BindingDB