Molecule Details
InChIKeyCWBWMDSAVFJNAD-UHFFFAOYSA-N
Compound Name6-(3-Aminophenyl)quinoline-8-carboxamide
Canonical SMILESNC(=O)c1cc(-c2cccc(N)c2)cc2cccnc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.33
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P08922 ROS1 Homo sapiens Human PF00041 PF07714 7.0 Ki ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.5 Ki ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 6.3 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.1 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.0 Ki ChEMBL