Molecule Details
| InChIKey | CVQAHSMQXIWVLD-UHFFFAOYSA-N |
|---|---|
| Compound Name | 8-Chloro-5-oxo-9-[1,2,4]triazol-4-yl-5,6-dihydro-pyrazolo[1,5-c]quinazoline-2-carboxylic acid |
| Canonical SMILES | O=C(O)c1cc2c3cc(-n4cnnc4)c(Cl)cc3[nH]c(=O)n2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.57 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P42261 | GRIA1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.6 | Ki | ChEMBL |
| P42262 | GRIA2 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.6 | Ki | ChEMBL |
| P42263 | GRIA3 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.6 | Ki | ChEMBL |
| P48058 | GRIA4 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.6 | Ki | ChEMBL |