Molecule Details
InChIKeyCVFYLUGNOLKEFO-UHFFFAOYSA-N
Compound NameN-{1-[6-(Phenylamino)pyrazin-2-Yl]-1h-Benzimidazol-6-Yl}prop-2-Enamide
Canonical SMILESC=CC(=O)Nc1ccc2ncn(-c3cncc(Nc4ccccc4)n3)c2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.29
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.1 IC50 ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.3 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.3 IC50 ChEMBL
Q06187 BTK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.2 IC50 ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.2 IC50 ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.0 IC50 ChEMBL
O75716 STK16 Homo sapiens Human PF00069 6.0 IC50 ChEMBL