Molecule Details
InChIKeyCUVLPOCXZYLQBD-UHFFFAOYSA-N
Compound Name3-[(1,3-Diphenylpyrazol-5-yl)amino]-1-(4-methoxyphenyl)prop-2-en-1-one
Canonical SMILESCOc1ccc(C(=O)C=CNc2cc(-c3ccccc3)nn2-c2ccccc2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.73
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 7.5 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.5 IC50 ChEMBL;BindingDB
P50613 CDK7 Homo sapiens Human PF00069 6.6 IC50 ChEMBL
P51946 CCNH Homo sapiens Human PF16899 PF00134 6.6 IC50 ChEMBL;BindingDB
P06493 CDK1 Homo sapiens Human PF00069 6.1 IC50 ChEMBL;BindingDB
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.1 IC50 ChEMBL