Molecule Details
InChIKeyCTJAMSGCMYAVCZ-UHFFFAOYSA-N
Compound Name4-(1H-indazol-5-yl)-N-phenylthiazol-2-amine
Canonical SMILESc1ccc(Nc2nc(-c3ccc4[nH]ncc4c3)cs2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL6.36
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.1 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.6 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.5 Ki ChEMBL;BindingDB
P49760 CLK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.1 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.1 Ki ChEMBL;BindingDB
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.1 Ki ChEMBL;BindingDB
Q15303 ERBB4 Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.0 Ki ChEMBL