Molecule Details
InChIKeyCSVXUAKTJJDCMS-UHFFFAOYSA-N
Compound NameN-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]-3-tert-butylbenzamide
Canonical SMILESCC(=O)Nc1cn2cc(-c3cc(NC(=O)c4cccc(C(C)(C)C)c4)ccc3C)ccc2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL8.61
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P15056 BRAF Homo sapiens Human PF00130 PF07714 PF02196 9.5 IC50 ChEMBL;BindingDB
O15264 MAPK13 Homo sapiens Human PF00069 8.7 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 8.7 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 8.7 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 8.7 IC50 ChEMBL;BindingDB
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.4 IC50 ChEMBL;BindingDB