4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesulfonamide

InChIKey	`CSHPDJRLDWXEIZ-UHFFFAOYSA-N`
Compound Name	4-((2,4-Diaminopteridin-6-yl)methylamino)benzenesulfonamide
Canonical SMILES	`Nc1nc(N)c2nc(CNc3ccc(S(N)(=O)=O)cc3)cnc2n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.46
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q16790	CA9	Homo sapiens	Human	PF00194	8.7	Ki	ChEMBL;BindingDB
P00918	CA2	Homo sapiens	Human	PF00194	8.3	Ki	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	8.3	pIC50	TTD_MultiTarget