Molecule Details
| InChIKey | CRZXYCJOVDIWGP-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[2-(dimethylamino)ethyl]-4-[[4-(4-fluoro-2-methoxyphenyl)-1,3,5-triazin-2-yl]amino]benzamide |
| Canonical SMILES | COc1cc(F)ccc1-c1ncnc(Nc2ccc(C(=O)NCCN(C)C)cc2)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.06 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O60563 | CCNT1 | Homo sapiens | Human | PF00134 PF21797 | 8.5 | IC50 | ChEMBL |
| P50750 | CDK9 | Homo sapiens | Human | PF00069 | 8.5 | IC50 | ChEMBL |
| P20248 | CCNA2 | Homo sapiens | Human | PF02984 PF00134 PF16500 | 7.6 | IC50 | ChEMBL |
| P24941 | CDK2 | Homo sapiens | Human | PF00069 | 7.6 | IC50 | ChEMBL |