4-[3-(4-N-Phenylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[3-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine

InChIKey	`CRVFIGQYZIENPM-UHFFFAOYSA-N`
Compound Name	4-[3-(4-N-Phenylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[3-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine
Canonical SMILES	`CCn1cc(-c2ccnc3[nH]c(-c4cccc(CN(C)C)c4)cc23)c(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.42
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.7	IC50	ChEMBL;BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	7.3	IC50	ChEMBL;BindingDB
O75716	STK16	Homo sapiens	Human	PF00069	7.3	pIC50	TTD_MultiTarget